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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERO1L
All Species:
45.15
Human Site:
Y248
Identified Species:
62.08
UniProt:
Q96HE7
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HE7
NP_055399.1
468
54393
Y248
C
V
E
K
R
A
F
Y
R
L
I
S
G
L
H
Chimpanzee
Pan troglodytes
XP_509950
468
54427
Y248
C
V
E
K
R
A
F
Y
R
L
I
S
G
L
H
Rhesus Macaque
Macaca mulatta
XP_001103965
468
54383
Y248
C
V
E
K
R
A
F
Y
R
L
I
S
G
L
H
Dog
Lupus familis
XP_547813
468
54343
Y248
C
V
E
K
R
A
F
Y
R
L
I
S
G
L
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8R180
464
54066
Y244
C
V
E
K
R
A
F
Y
R
L
I
S
G
L
H
Rat
Rattus norvegicus
Q8R4A1
464
54000
Y244
C
V
E
K
R
A
F
Y
R
L
I
S
G
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515503
465
53870
Y245
C
V
E
K
R
A
F
Y
K
L
I
S
G
L
H
Chicken
Gallus gallus
XP_421473
463
52908
Y243
C
V
E
K
R
A
F
Y
R
L
I
S
G
L
H
Frog
Xenopus laevis
Q6DD71
465
53720
Y246
C
V
E
K
R
A
F
Y
R
L
I
S
G
L
H
Zebra Danio
Brachydanio rerio
Q7T3D1
489
56571
F239
C
V
E
K
R
A
F
F
R
L
I
S
G
L
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3A6
483
55641
Y258
C
L
E
Q
R
A
F
Y
R
I
I
S
G
L
H
Honey Bee
Apis mellifera
XP_623933
471
55049
Y250
C
L
E
K
R
V
F
Y
R
V
I
S
G
L
H
Nematode Worm
Caenorhab. elegans
Q7YTU4
478
55136
L243
F
Y
R
L
I
S
G
L
H
S
A
I
T
I
S
Sea Urchin
Strong. purpuratus
XP_796844
897
101920
R674
L
E
K
R
V
F
Y
R
L
I
S
G
L
H
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C7S7
469
53812
N268
S
R
N
Q
W
G
Q
N
I
E
L
M
Y
D
R
Baker's Yeast
Sacchar. cerevisiae
Q03103
563
65014
G248
E
Y
L
N
T
K
T
G
K
W
E
P
N
L
D
Red Bread Mold
Neurospora crassa
Q7SEY9
668
75589
L247
A
A
G
R
Q
H
M
L
E
Q
Q
R
E
Q
N
Conservation
Percent
Protein Identity:
100
99.5
98.7
96.3
N.A.
91.8
91.4
N.A.
84.6
77.7
70.9
62.1
N.A.
46.1
48.4
41.4
29.3
Protein Similarity:
100
99.5
99.3
97.8
N.A.
95.9
95.7
N.A.
90.1
85.4
83.9
75.4
N.A.
64.1
65.6
60.8
37.6
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
100
100
93.3
N.A.
80
80
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
100
93.3
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.9
22.5
22.1
Protein Similarity:
N.A.
N.A.
N.A.
55.6
41.2
38
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
6
0
0
0
65
0
0
0
0
6
0
0
0
0
% A
% Cys:
71
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
6
% D
% Glu:
6
6
71
0
0
0
0
0
6
6
6
0
6
0
0
% E
% Phe:
6
0
0
0
0
6
71
6
0
0
0
0
0
0
0
% F
% Gly:
0
0
6
0
0
6
6
6
0
0
0
6
71
0
0
% G
% His:
0
0
0
0
0
6
0
0
6
0
0
0
0
6
71
% H
% Ile:
0
0
0
0
6
0
0
0
6
12
71
6
0
6
0
% I
% Lys:
0
0
6
65
0
6
0
0
12
0
0
0
0
0
0
% K
% Leu:
6
12
6
6
0
0
0
12
6
59
6
0
6
77
0
% L
% Met:
0
0
0
0
0
0
6
0
0
0
0
6
0
0
0
% M
% Asn:
0
0
6
6
0
0
0
6
0
0
0
0
6
0
6
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% P
% Gln:
0
0
0
12
6
0
6
0
0
6
6
0
0
6
0
% Q
% Arg:
0
6
6
12
71
0
0
6
65
0
0
6
0
0
6
% R
% Ser:
6
0
0
0
0
6
0
0
0
6
6
71
0
0
12
% S
% Thr:
0
0
0
0
6
0
6
0
0
0
0
0
6
0
0
% T
% Val:
0
59
0
0
6
6
0
0
0
6
0
0
0
0
0
% V
% Trp:
0
0
0
0
6
0
0
0
0
6
0
0
0
0
0
% W
% Tyr:
0
12
0
0
0
0
6
65
0
0
0
0
6
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _